Run the 100 or 200 or both?

In this set up…

tues: meet (100 or 200/both?)
wed: rest
thurs: 3x30 + 1x50m sub max
fri: rest
sat: major meet

Can I run both events? My personal bests are in low 11s and 23s but Im wondering if doing both can really impact me cause someone I know ran a 400 in low 48, 4 days out and last weekend ran a 10.5/21.1.

Any thoughts?