Thanks, I will try to post more when I find it. Good to have a localized source for these sorts of things, and these long lecture type videos are great educational resources.
Just something I’ve been reading about these days, the mTOR pathway:
"When mTOR is activated, it causes muscle cells to increase protein synthesis. This leads to skeletal muscle hypertrophy. mTOR integrates cellular information regarding intracellular nutrient status and energy and oxidative stress levels. When it deems that energy levels are high and the muscle cells are stressed, it activates in order to help the cells heal and rebuild in a stronger manner.
mTOR is activated by certain factors such as insulin, growth factors (IGF-1 & IGF-2), oxidative stress, mechanical overloading and amino acids. mTOR is part of the insulin pathway, and normalized function depends upon healthy cellular insulin sensitivity. Elevated circulating insulin levels cause a rapid increase in mTOR. However, as people begin to lose normal cellular insulin sensitivity, they also lose the ability to effectively utilize mTOR." - Dr. David Jockers
Learn more: http://www.naturalnews.com/033957_muscle_growth_proteins.html#ixzz1bjl347lw
As my own experience has shown, having great insulin sensitivity makes you more anabolic, through this particular pathway. Taking advantage of the insulin response post workout seems to be quite key. Along with some BCAA’s pre, mid and post workout to continue the protein synthesis signal.