The same as any other drill/exercise, I reserve the use of any particular activity for athletes who are able to perform them effectively enough to generate quality outputs in an orthopedically sound fashion.
I’ve had mixed results with the throw + sprint and hop + throw + sprint. I’ve used them all; however, not with all my athletes as some athletes just don’t have the awareness and coordination to make them, in my view, worth while.
Bottom line, if someone can do it well and it makes sense in the programming then proceed; if not, find something else.